Fig. 1: Structure of substrate-bound p97–p47 complex. | Nature Communications

Fig. 1: Structure of substrate-bound p97–p47 complex.

From: Active conformation of the p97-p47 unfoldase complex

Fig. 1

a Domain organization of p97 and p47. Domains are labeled and residue ranges indicated. b Top and side views of high-threshold segmented map and refined model (subunits A-F of p97 labeled). The substrate peptide density and model are colored magenta. c Model of the complete p97 complex including N domains modeled in the ‘up’ conformation. d Model of a p97 protomer (subunit D shown) with the associated p47 UBX domain. Orientation corresponds to the side view on panel (b). e Low threshold density fitted with a p97 N domain and p47 UBX domain.

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