Fig. 2: Correlation analysis of the transcriptome and proteome and allocation of the transcriptome into different functional categories. | Nature Communications

Fig. 2: Correlation analysis of the transcriptome and proteome and allocation of the transcriptome into different functional categories.

From: Proteome allocations change linearly with the specific growth rate of Saccharomyces cerevisiae under glucose limitation

Fig. 2

A Perfect monotone (with Spearman correlation coefficient R = 1) correlations between absolute protein and mRNA abundance at the individual gene level across different growth rates, illustrated with the three genes CTA1, GPX1, and HYR1. These three genes are chosen here since they stand out when performing GO term enrichment analysis and commonly fall into three GO function terms. B Distribution of Spearman rank correlation coefficients for individual proteins vs. their corresponding mRNA levels across different specific growth rates. Here, FDR < 0.05 was used to distinguish between significant correlation (in orange) and random correlation (in blue). C Changes in the fraction of mRNAs allocated to translation, mitochondrial, and amino acid biosynthesis across different specific growth rates. D Changes in the fraction of mRNAs allocated to chaperones, glycolysis, and lipid metabolism across different specific growth rates. Source data are provided as a Source Data file.

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