Fig. 5: In vivo pharmacokinetic response to additional peptide-loaded microspheres. | Nature Communications

Fig. 5: In vivo pharmacokinetic response to additional peptide-loaded microspheres.

From: Efficient aqueous remote loading of peptides in poly(lactic-co-glycolic acid)

Fig. 5

Pharmacokinetics after single subcutaneous injections of Sandostatin LAR® (a), and remote-loaded microspheres containing octreotide (b), bremelanotide (c), and salmon calcitonin (d) in male Sprague-Dawley rats. Rats in the octreotide and bremelanotide groups were administered a dose of 18 mg/kg. Rats in the salmon calcitonin group were dosed at 4 mg/kg. Data are presented as mean values ± SEM (n = 4 rats).

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