Fig. 3: Scope of amidine hydrochlorides and primary alcohols. | Nature Communications

Fig. 3: Scope of amidine hydrochlorides and primary alcohols.

From: Transition-metal-free synthesis of pyrimidines from lignin β-O-4 segments via a one-pot multi-component reaction

Fig. 3

Conditions: 1a (0.4 mmol), 2 (0.2 mmol), 3 (0.4 mmol), NaOH (1.6 mmol), tert-amyl alcohol (abbreviation: t-AmOH, 4.0 mL) were mixed in the air at 110 °C, t = 20 h; the yields of 4 and 5a were calculated based on the amount of 2 and 1a, respectively. aIsolated molar yield; bGC molar yield was determined by GC-FID using mesitylene as an internal standard.

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