Fig. 6: Radical quenching.
From: Catalytic activity imperative for nanoparticle dose enhancement in photon and proton therapy
Impact of DMSO (hydroxyl radical scavenger) on the surviving fraction (SF) of HT1080 cells with and without nanoparticles after irradiation with 6 Gy of 150 kVp X-rays. Cells have been pre-incubated with 160 µg/mL TiO2 (a), 80 µg/mL TiN (b), 160 µg/mL WO3 (c), 320 µg/mL HfO2 (d), and 40 µg/mL Au nanoparticles (e) for 24 h before DMSO and X-ray treatment. Monodose nanoparticle enhancement ratio (NER) at 6 Gy without and with 1 M DMSO (f). Data in a–f expressed as mean ± SD from n = 8 biological replicates examined over 2 independent CellTiter Glo experiments for each nanoparticle type or vehicle.
