Table 2 Substrate scope for cycloaddition of SCBs with alkynesa.

From: Nickel(0)-catalyzed divergent reactions of silacyclobutanes with internal alkynes

  1. aInternal alkynes 2 (0.2 mmol), SCBs 1 (0.6 mmol), Ni(cod)2 (0.02 mmol), IPr•HCl (0.024 mmol), and LiOtBu (0.04 mmol) in toluene (1.0 ml) at 120 °C for 24 h. Values represent isolated yields.
  2. bAlkynes were slowly added to the mixture of the catalyst and SCBs at 100 °C via syringe driver over 6 h.
Back to article page