Table 1 Initial reaction development^a.

TFE 2,2,2- trifluoroethanol, TsOH p-toluenesulfonic acid.
^aReaction conditions: [Ir]/L/1/2 = 1:2.1:100:100; 1 0.1 mmol, solvent 2 mL, r.t., 24 h. Yields and enantiomeric excesses were determined by chiral HPLC after the products were converted to the corresponding acetamides.
^bThe amount of the added additives was 10 mol%.
^cThe 3-phenylpropylamine hydrochloride salt (30 mol%) was used instead of FeCl₃.
^dThe catalyst loading was 0.05 mol%. The reaction temperature was 40 ^oC. FeCl₃ was 30 mol%.
^eThe catalyst loading was 0.02 mol%. The reaction temperature was 60 ^oC. FeCl₃ was 30 mol%.

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