Fig. 7: Compartmentalized infections establish replication islands within the lung.

a Overlap between barcodes in the nasal wash 3 dpi and those present in distinct lobes, or composite data for all barcodes in the lung. b–d The frequency of barcodes within the nasal wash is compared to frequencies within individual lobes for b ferret 34, c ferret 35, and d ferret 36. Red arrowheads highlight dominant barcodes with frequency >30%, which for ferret 36 is the same barcode that dominated in multiple lobes of the lung. Note that barcodes unique to the nasal wash or lung are not plotted here and can be found in Supplemental Fig. 6. Source data are provided as a Source Data file.