Fig. 6: ATG7-independent mitochondria clearance is impaired when autophagic secretion of mitochondria is inhibited. | Nature Communications

Fig. 6: ATG7-independent mitochondria clearance is impaired when autophagic secretion of mitochondria is inhibited.

From: A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery

Fig. 6: ATG7-independent mitochondria clearance is impaired when autophagic secretion of mitochondria is inhibited.The alt text for this image may have been generated using AI.

a WT, ATG7-KO, and ATG14/ATG7 DKO HeLa stably expressing mCherry-Parkin were treated with A/O for the indicated duration and immunoblotted for proteins from different mitochondria compartments. b ATG7-KO and FIP200/ATG7 DKO cells were treated with A/O for the indicated duration. c ATG7-KO cells stably expressing mCherry-Parkin was treated with A/O, with or without SBI- 0206965 (25 µM). d ATG7-KO and ATG9A/ ATG7 were treated with A/O for the indicated duration. e ATG7-KO and RAB7A/ATG7 DKO cells were treated with A/O for the indicated duration.

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