Fig. 7: Splicing regulation of GPHN expression in 21 human tissues.
From: Complex regulation of Gephyrin splicing is a determinant of inhibitory postsynaptic diversity
A Procedure and number of sequences obtained by long-read sequencing with the Oxford Nanopore technology. Amplification of GPHN transcriptome from each 21 human tissues was processed independently and mixed in a multiplexed library. B Distribution and percentages of alternative transcripts expressed by GPHN in the human body. C Graphical representation showing the proportion of splice variants that were detected in all tissues (core of common 226 alternative transcripts) and those distinctly expressed in one or more tissue(s). D Graphical representation of global expression level of GPHN in 16 distinct human tissues using the data provided by the Genotype-Tissue Expression (GTEx) project (https://gtexportal.org/home/). E Heat map graphical representation of the 60 most expressed GPHN transcripts in adult and fetal human brain, as well as the whole brain versus the cerebellum. The yellow color indicates an identical expression level between samples, while the blue scale shows a decrease and the pink an increase. Source data is provided as a Source Data file.
