Table 1 Optimization of the reaction conditions.
From: A practical fluorosulfonylating platform via photocatalytic imidazolium-based SO2F radical reagent
Entry | Variation from the conditions | Yield of 3aa/% | E:Z of 3ab |
|---|---|---|---|
1 | None | 62 | >20:1 |
2 | 2b instead of 2a | 71 (65)c | >20:1 |
3 | 2c instead of 2a | 58 | >20:1 |
4 | 2d instead of 2a | 64 | >20:1 |
5 | 2e instead of 2a | 16 | >20:1 |
6 | Ir(ppy)3 instead of 4CzIPN | 59 | >20:1 |
7 | Other solvents instead of DME | 0–41% | >20:1 |
8 | w/o KH2PO4 | 45 | >20:1 |
9 | w/o 4CzIPN | 0 | — |
10 | In the darkness | 0 | — |
