Fig. 3: Experimental results and dwell time analysis for two cavity confined DNA chains of equal size. | Nature Communications

Fig. 3: Experimental results and dwell time analysis for two cavity confined DNA chains of equal size.

From: Confinement anisotropy drives polar organization of two DNA molecules interacting in a nanoscale cavity

Fig. 3

a, b Time series of separation vector projected along the semi-major axis (red-curve) for e = 0.6 and e = 0.9 respectively. The projections are normalized to half the cavity extent, so localization of the configuration in a polar proximal free energy well corresponds to a value close to ±1. The black dashed line shows the baseline of two states. The green solid lines indicate the time corresponding to the adjoining image. In a, the two chains attempt to flip but fail to do so, forming a spike in the vector projection. In b, the two chains flip successfully, reversing the sign of the vector projection. The scale bars are 1 μm. c Histogram of the dwell time for four eccentricities; overlaid dashed lines correspond to exponential fits. d Mean dwell time verses cavity eccentricity, with the mean dwell time extracted from exponential fitting to the corresponding cumulative distributions. The error bars denote the fitting covariance.

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