Fig. 4: Clinical course and diagnostic timeline of two critically ill infants who received 13.5-h rWGS and confirmatory standard diagnostic rWGS.

Clinical (a and c, dark blue circles) and diagnostic timelines (b and d, light blue circles) of infants AH638 (a, b) and CSD59F (c, d), who received both standard, clinical rWGS and the 13.5-h methods. ED Emergency Department, EEG Electroencephalogram, AI Artificial intelligence, DOL Day of life. Circles with vertical lines indicate interactions between neonatology, genomics, and biochemical genetics.