Fig. 3: Characterization of CF sites from human HCC tumor and normal tissues using the STAGE method. | Nature Communications

Fig. 3: Characterization of CF sites from human HCC tumor and normal tissues using the STAGE method.

From: Characterization of core fucosylation via sequential enzymatic treatments of intact glycopeptides and mass spectrometry analysis

Fig. 3: Characterization of CF sites from human HCC tumor and normal tissues using the STAGE method.

a Number of identified CF sites in tumor and normal liver tissues. b MS/MS spectrum of the CF glycopeptide, N240GTGHGN246STHHGPEYMR from hemopexin (UniProt ID: P02790). The site, N240, was modified by CF biantennary glycans, whereas the site, N246, was a glycosite that was modified by other glycans. Keys: b-HexNAc(1)dHex(1) represents a disaccharide, HexNAc(1)dHex(1), is lost from this b ion; y-HexNAc(1)dHex(1) represents a disaccharide, HexNAc(1)dHex(1), is lost from this y ion; b-HexNAc(1) represents a monosaccharide residue, HexNAc(1), is lost from this b ion; y-HexNAc(1) represents a monosaccharide residue, HexNAc(1), is lost from this y ion.

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