Fig. 5: Quantitative analysis of glycosites from HCC tumor (Tumor) and normal (Normal) tissues by TMT labeling coupled with the STAGE method. | Nature Communications

Fig. 5: Quantitative analysis of glycosites from HCC tumor (Tumor) and normal (Normal) tissues by TMT labeling coupled with the STAGE method.

From: Characterization of core fucosylation via sequential enzymatic treatments of intact glycopeptides and mass spectrometry analysis

Fig. 5: Quantitative analysis of glycosites from HCC tumor (Tumor) and normal (Normal) tissues by TMT labeling coupled with the STAGE method.

a Differential expression of glycosylation sites containing ≥1 CF sites between Tumor and Normal tissues. Glycosylation sites that were up- and down-regulated (FDR < 0.01 and fold change ≥1.5) in tumor relative to normal tissues are highlighted in pink and blue, respectively, of which glycosites from liver tissue/cancer-related glycoproteins are highlighted in darker colors. b KEGG pathway assignment based on upregulated proteins. Source data are provided as a Source Data file.

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