Table 2 Threshold effect analysis of the association between FLT3/ITD AR and risk of all-cause mortality using piece-wise linear regression.

From: Poor outcome of pediatric patients with acute myeloid leukemia harboring high FLT3/ITD allelic ratios

FLT3/ITD AR

Crude

Adjusta

LogRR (95% CI)

P value

LogRR (95% CI)

P value

<0.5

2.0 (0.9, 4.4)

0.088

45.1 (0.9, 2281.6)

0.057

≥0.5

1.0 (0.9, 1.1)

0.715

1.6 (1.1, 2.3)

0.013

  1. Crude: none adjustment.
  2. aAdjusted: adjustments were made for multiple comparisons, including Gender; Chemotherapy Protocol; Risk group; BM blast; Peripheral blood blasts; CNSL; FAB Category; Karyotype; WBC group; Age group; CEBPA status; WT1 status; NPM1 status.