Fig. 6: Real-time monitoring of the tumor vascular disruption after treatment with combretastatin A4 phosphate (CA4P).
From: Acceptor engineering for NIR-II dyes with high photochemical and biomedical performance
a Schematic illustration of the tumor vascular disruption process after treatment with CA4P. b After 30 min administration of PBS, tumor vasculatures NIR-II imaging of nude mice with 143B xenograft osteosarcoma were obtained at different time points after FT-TQT@FBS p.i. c After 30 min administration of CA4P, tumor vasculatures NIR-II imaging of nude mice with xenograft osteosarcoma 143B was obtained at different time points after FT-TQT @FBS p.i. d Cross-sectional (solid line) and Gaussian fit fluorescence intensity profiles (dotted black line) of the vessel along the dashed yellow lines in c at different time points. Scale bar: 1 mm. Norm, Normalized. The detailed imaging parameters for each image are listed in Supplementary Table 3.
