Table 1 Antibiotic activity of benazepril against Mtb. M. tuberculosis H37Rv was cultured in 7H9 medium with the indicated treatment.
From: Low-cost anti-mycobacterial drug discovery using engineered E. coli
Compound | Dilution range | MIC |
|---|---|---|
DCS | 0–2.0 mM | 0.125 mM |
DCS + 5 mM D-ala | 0–2.0 mM | >2 mM |
Benazepril | 0–4.5 mM | 2.25–4.5 mM |
Benazepril + 5 mM D-ala | 0–4.5 mM | 2.25 mM |
Benazeprilat | 0–0.5 mM | >0.5 mM |
Isoniazid | 0–30 μM | 0.3 μM |
DMSO | 0–5% | >5% |
