Fig. 3: Monomer interactions in Cry11Aa and Cry11Ba.

a Cry11Aa crystal packing, colored according to sequence (from blue to red) indicating the domain-based assembly; and colored according to tetramer assembly (see panel (b)). The highlighted areas indicate the regions shown in (b) (full line) and (c) (dashed line). b Cry11Aa tetramer with zoom on each of the three interfaces identified by PISA (interface #1, #3 and #6), with the involved residues depicted as spheres. Supplementary Fig. 5 shows the residues involved in hydrogen bonds and salt bridges. c Cry11Aa crystal assembly by interactions between neighboring tetramers, formed by interface #2, #4 and #5, visualized as in (b). d, Cry11Ba crystal packing, colored as in (a). e Cry11Ba tetramer with zoom on the interfaces as in (b). f Cry11Ba crystal assembly, visualized as in (c). As compared to Cry11Aa, Cry11Ba crystals contain an additional interface #7 between an A-B pair from two neighboring tetramers. g Interface statistics as identified by PISA for Cry11Aa (blue) and Cry11Ba (red).