Fig. 2: Transcriptomic landscape of A. castellanii encystment in vitro.
From: A time-resolved multi-omics atlas of Acanthamoeba castellanii encystment
a Modules of the differentially expressed transcripts. The dot plot is color-coded with the mean of log2-transformed fold change relative to the control condition (T0) for each module during encystment and in the control condition (1, 4, 8 h). The size of each dot is proportional to the number of transcripts per cluster (indicated on the right). b Functional annotations retrieved with eggNOG-mapper and significantly enriched in the given expression modules. The module median kinetics in the encystment condition are represented in the middle (upregulation and downregulation in the red and blue area, respectively). The detailed outputs of the enrichment can be found in Supplementary Data 2 file. “*”: maturation of 5.8S rRNA; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
