Fig. 2: Reaction optimization and mechanistic rationalization.
From: Divergent synthesis of benzazepines and bridged polycycloalkanones via dearomative rearrangement
a Serendipitous discovery and reaction optimization. b Rationalization of the mechanism of the serendipitously observed 2a. c Selected representative drug molecules and important bioactive benzazepine scaffolds. Ts = p-toluenesulfonyl. Bn = benzyl.
