Fig. 6: Dependence of the overall fit (RMSE) on the individual fit flipping parameters in the PUF4 and PUM2 models. | Nature Communications

Fig. 6: Dependence of the overall fit (RMSE) on the individual fit flipping parameters in the PUF4 and PUM2 models.

From: A comprehensive thermodynamic model for RNA binding by the Saccharomyces cerevisiae Pumilio protein PUF4

Fig. 6

Parameter sensitivity for flipping terms (ΔΔGfY; see Fig. 3a) for the PUF4 model were calculated as in Fig. 5 (green curves, right axis). PUM2 parameter sensitivities were replotted from ref. 34 (blue curves, left axis). Vertical dashed blue and green lines indicate the best fit values for each model (PUM2 and PUF4, respectively) and were similar to the minima obtained in the sensitivity analysis.

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