Table 1 Thermodynamic parameter values for the PUF4 additive non-consecutive model

From: A comprehensive thermodynamic model for RNA binding by the Saccharomyces cerevisiae Pumilio protein PUF4

Term I

ΔΔGbX (kcal/mol)

    
 

X =

    

Bound residue position b =

A

C

U

G

 

1

3.69

2.85

0.00

3.97

 

2

2.50

4.41

4.39

0.00

 

3

2.67

3.01

0.00

2.52

 

4

0.00

2.29

1.75

1.51

 

5

0.89

0.03

0.00

1.10

 

6

0.00

0.93

0.85

1.41

 

7

2.48

1.82

0.00

2.07

 

8

0.00

1.47

1.33

1.33

 

9

0.60

0.37

0.00

0.24

 

Term II

ΔΔGfY (kcal/mol)

    
 

Y =

    

Flipped residue position f =

A

C

U

G

NNa

3/4

1.63

1.51

1.60

1.21

>1.50b

4/5

>2.00

1.36

1.75

>2.00

>1.50

5/6

>2.00

1.83

1.68

>2.00

>1.50

6/7

−1.15

−1.07

−1.34

−0.35

0.67

  1. a2-nt flip of any sequence.
  2. b>indicates a lower limit.