Table 3 Klebsiella genotype association with infection
Genotype | Case frequency | Control frequency | Unadjusted | Adjusted for clinical variables | ||
|---|---|---|---|---|---|---|
Odds ratio | P-value | Odds ratio | P-value | |||
Virulence determinants | Ā | Ā | Ā | Ā | Ā | Ā |
ybt | 0.207 | 0.133 | 1.7 | 0.144 | 1.78 | 0.155 |
col | 0.024 | 0.007 | 3.72 | 0.286 | 0.629 | 0.709 |
iuc | 0.024 | 0.007 | 3.72 | 0.286 | 0.436 | 0.507 |
iro | 0.012 | 0.007 | 1.84 | 0.668 | 0.476 | 0.602 |
rmpA | 0.024 | 0.007 | 3.72 | 0.286 | 0.436 | 0.507 |
rmpA2 | 0.012 | 0.007 | 1.84 | 0.668 | 0.937 | 0.964 |
AMR determinants* | Ā | Ā | Ā | Ā | ||
AGly acquired (aminoglycosides) | 0.268 | 0.067 | 5.133 | 7.01E-05 | 3.77 | 0.00427 |
Flq (fluoroquinolones) | 0.220 | 0.040 | 6.75 | 1.14E-04 | 6.69 | 0.000507 |
MLS (macrolides) | 0.098 | 0.013 | 8.0 | 0.010 | 6.41 | 0.0649 |
Phe (phenicols) | 0.171 | 0.027 | 7.51 | 0.001 | 6.35 | 0.00332 |
Rif (rifampin) | 0.012 | 0.000 | N/A | N/A | N/A | N/A |
Sul (sulfonamides) | 0.268 | 0.047 | 7.49 | 1.22E-05 | 5.19 | 0.00226 |
Tet (tetracyclines) | 0.183 | 0.100 | 2.01 | 0.076 | 1.88 | 0.128 |
Tmt (trimethoprim) | 0.244 | 0.053 | 5.73 | 8.86E-05 | 4.28 | 0.00285 |
Omp mutation | 0.037 | 0.020 | 1.86 | 0.453 | 1.55 | 0.676 |
Bla (β-lactamase that is āotherā) | 0.573 | 0.520 | 1.24 | 0.438 | 1.27 | 0.379 |
Bla Carb (carbapenemase) | 0.061 | 0.007 | 9.68 | 0.040 | 36.2 | 0.00151 |
Bla ESBL (extended-spectrum β-lactamases) | 0.207 | 0.087 | 2.76 | 0.011 | 2.94 | 0.0116 |
Bla broad (broad-spectrum β-lactamases) | 0.354 | 0.347 | 1.03 | 0.915 | 0.902 | 0.734 |
Bla broad inhR (broad-spectrum β-lactamases with resistance to β-lactamase inhibitors) | 0.110 | 0.107 | 1.03 | 0.942 | 1.05 | 0.922 |