Fig. 3: Stacked regional association plots at ELF5.
From: ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19
Each panel contains regional association statistics from linear regression analysis (p values) for the trait listed in the upper left corner along genomic coordinates. Each dot represents a single nucleotide polymorphism and colours indicate linkage disequilibrium (LD; r²) with the most likely causal variant (rs766826) at this locus (darker colours stronger LD). The position of rs766826 in the genome is highlighted by a red line on the lowest panel. Summary statistics for COVID-19-related outcomes were obtained from the COVID-19 HGI15, for protein abundances from Pietzner et al.30, and gene expression in lungs from GTEx version 835. LD was calculated based on 8350 unrelated white-British participants of the Fenland cohort.
