Fig. 6: SIRT2 suppresses Shigella autophagosome escape.
From: Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation
A Effect of SIRT2 knockout on S. flexneri autophagosome escape. Representative images of MEF cells infected with S. flexneri from three biological replicates are shown. Scale bar: 15 μm. White arrow: LC3-positive Shigella. B Quantitation of data shown in A. Percentage of MEF cells containing LC3-positive shigella was quantified. n = 3 biological replicates. Data is shown as mean ± SEM with >100 infected MEF cells counted for each experiment. Statistical evaluation was done using two-way ANOVA. Data are represented as mean ± SEM.
