Fig. 8: The significance of valence.
From: Reactivating hippocampal-mediated memories during reconsolidation to disrupt fear
a Reactivation of a competing positive memory via optical stimulation is sufficient to update a fear memory during reconsolidation. Reactivation of an engram associated with a negative experience, or a neutral experience with the exception of exposure to a novel clean cage, was not able to diminish freezing when assessed immediately after stimulation, upon stress-induced reinstatement, or spontaneous recovery. Source data are provided as a Source Data file.
