Fig. 2: A lipid-filled central pore in ChRmine.
From: Cryo-EM structures of the channelrhodopsin ChRmine in lipid nanodiscs
a View from the membrane plane of the ChRmine central pore (yellow) against the surface of two channel subunits (the front subunit is not displayed). Corresponding pore radius as a function of distance from the intracellular side is shown on the same scale. b Overlay of a ChRmine and a C1C2 subunit. The uniquely structured ECL1 and N-terminal region of ChRmine line the central pore. c Constrictions of the central pore formed by lipids and ECL1 viewed from the membrane plane and d from the intracellular side. e Electrostatic character of the central pore drawn on the ChRmine surface in the same view as (a).
