Fig. 8: Model for the involvement of R-coils in INP multimerization.
From: Water-organizing motif continuity is critical for potent ice nucleation protein activity
a AlphaFold model for PbINP without its N-terminal domain. Water-organizing coils are shown in green, R-coils in blue, and the C-terminal domain in gold. b With full-length INPs, interactions between R-coils and water-organizing coils enable the formation of a large, wide surface. c A decrease in water-organizing coil numbers reduces the length of the ice-nucleating surface. d Loss of a critical number of R-coils leads to a breakdown in multimerization.
