Table 2 PDXs and corresponding patient tumor characteristics

From: Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

PDX

Age at Surgery

Tumor Type

ER%

PR%

HER2%

Ki67%

Treatment

Generation in Mice

T70

39

NST, Primary

negative

negative

negative

>90

untreated

6 to 8

T99

57

NST, Primary

57

70

negative

20

untreated

6 to 8

METS15

59

NST, Ascites

90

100

negative

N/A

chemo, AI, fulvestrant

2 to 4

  1. NST no special type, N/A not applicable, chemo chemotherapy, AI aromatase inhibitors.