Table 2 Immunization scheme and n = biological independent samples analyzed in the assays indicated

1st vaccination

ChAd

ChAd

ChAd

ChAd

ChAd

ChAd

ChAd

ChAd

ChAd

ChAd

BNT

BNT

BNT

BNT

BNT

2nd vaccination

-----

ChAd

ChAd

ChAd

ChAd

-----

BNT

BNT

BNT

BNT

-----

BNT

BNT

BNT

BNT

3rd vaccination

-----

-----

-----

-----

BNT

-----

-----

-----

-----

BNT

-----

-----

-----

-----

BNT

Time after last vaccination

2 mo

14d

4 mo

6mo

14d

2 mo

14d

4 mo

6mo

14d

21d

1mo

7 mo

9 mo

21d

Anti-S1-IgG

Fig. 1b, c

41

39

37

26

29

80

80

73

61

61

37

38

49

14

24

Spike-specific B cells

Fig. 1d

41

35

32

25

28

83

74

68

59

61

n.d.

n.d.

n.d.

n.d.

n.d.

sVNT Wuhan

Fig. 2a, Suppl. Fig. 5a

40

39

37

26

27

82

79

73

60

59

34

47

33

48

24

sVNT Alpha

Fig. 2b, Suppl. Fig. 5b

40

39

37

26

27

82

79

73

60

59

34

47

33

48

24

sVNT Beta

Fig. 2b, Suppl. Fig. 5b

40

39

37

26

27

82

79

73

60

59

34

47

33

48

24

sVNT Gamma

Fig. 2b, Suppl. Fig. 5b

40

39

37

26

27

82

79

73

60

59

34

47

33

48

24

sVNT Delta

Fig. 2a, Suppl. Fig. 5a

40

39

37

26

27

82

79

73

60

59

34

47

33

48

24

sVNT Omicron

Fig. 2a, Suppl. Fig. 5a

n.d.

39

n.d.

26

27

n.d.

79

n.d.

60

59

n.d.

44

n.d.

48

24

Spike-specific CD4 cells

Fig. 3a, Suppl. Fig. 7

41

35

32

25

28

82

74

68

59

61

n.d.

n.d.

n.d.

n.d.

n.d.

Spike-specific CD8 cells

Fig. 3b, Suppl. Fig. 7

41

34

32

25

28

82

67

68

59

63

n.d.

n.d.

n.d.

n.d.

n.d.

IGRA

Fig. 3c

27

24

20

24

16

60

53

42

56

43

n.d.

n.d.

n.d.

n.d.

n.d.