Table 4 Symptom outcomes by bamlanivimab dose cohort and treatment arm
7000 mg dose cohort | 700 mg dose cohort | |||||
|---|---|---|---|---|---|---|
Bamlanivimab (N = 48) | Placebo (N = 46) | p-value | Bamlanivimab (N = 111) | Placebo (N = 112) | p-value | |
Time to symptom improvement from study entry (primary symptom outcome), median (IQR), days | 21.0 (7.0, 28.0) | 18.5 (7.0, 28.0) | 0.97a | 24.0 (14.0, 28.0) | 20.5 (9.0, 28.0) | 0.08a |
Proportion of participants with at least 1 symptom reported as more severe than at study entry in study diary, n (%) | 42 (87.5) | 40 (87.0) | 0.94b | 102 (91.9) | 105 (93.8) | 0.59b |
Symptom severity ranking (AUC of total symptom score days 0–28), median (IQR) | 1.38 (0.93, 3.09) | 1.88 (1.09, 3.05) | 0.14a | 2.34 (1.30, 3.93) | 2.13 (1.06, 4.08) | 0.65a |