Fig. 5: ATP binding displaces the O antigen from the CBD. | Nature Communications

Fig. 5: ATP binding displaces the O antigen from the CBD.

From: Molecular basis for polysaccharide recognition and modulated ATP hydrolysis by the O antigen ABC transporter

Fig. 5: ATP binding displaces the O antigen from the CBD.

a, b Representative 2D and 3D classes of WzmWzt conformational states identified during ATP hydrolysis. c Cartoon model of WzmWzt bound to ADP:Mg2+ and O antigen. Domains are colored as shown in Fig. 3. The O antigen density is colored green. O antigen and ADP are presented as sticks and Mg2+ as a lime sphere. Zoom window: Local map of the O antigen binding site for CBD1-a in the ADP-bound map contoured at 7.2σ. d Cartoon model of WzmWzt bound to ATP:Mg2+. ATP is presented as sticks and Mg2+ as a lime sphere. Zoom window: Local map of the O antigen binding site for CBD1-a in the ATP-bound map contoured at 7.7σ.

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