Fig. 1: Representative epoxide ring-opening reactions. | Nature Communications

Fig. 1: Representative epoxide ring-opening reactions.

From: Flavin-enabled reductive and oxidative epoxide ring opening reactions

Fig. 1: Representative epoxide ring-opening reactions.The alternative text for this image may have been generated using AI.

a Nonenzymatic epoxide ring-opening reactions involving addition of a nucleophile (Nuc) under basic or acidic conditions. b Enzymatic epoxide ring-opening reactions by epoxide hydrolases (EHs) and oxidoreductases (ORs). c Epoxide ring-opening reactions of fluostatin C (1), either enzymatically catalyzed by the hydrolase Alp1U, or nonenzymatically mediated by FAD and NADH as reported in this study.

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