Fig. 1: Study biopsy and clinical information.

a Study schematic. b Sankey diagram showing site of biopsy at baseline (left) and at progression (right). Values indicate number of biopsies performed on each type of tissue at baseline (left) or progression (right). c Left panel shows PSA change at 12 weeks for each patient. Right panel shows time between biopsies for each patient. Response indicates whether a patient experienced a ≥ 50% reduction in PSA level at 12 weeks vs. baseline. For subject 022, PSA information was not available. Source data are provided as a Source Data file.