Table 3 Multivariate Cox regression analyses for disease-free survival and overall survival in patients with gastric cancer in the external validation cohort

 RS

1.180 (1.013–1.373)

1.167 (1.003–1.358)

 Age (≥60 vs. <60 years)

1.269 (1.028–1.565)

1.263 (1.023–1.558)

 Cardia

0.841 (0.567–1.246)

0.731 (0.496–1.976)

 Body

0.467 (0.308–0.708)

0.443 (0.294–0.668)

 Antrum

0.572 (0.386–0.845)

0.503 (0.342–0.740)

 Whole

Reference

Reference

 CA19-9 (elevated versus normal)

1.553 (1.242–1.943)

1.563 (1.248–1.957)

 Lauren type (diffuse or mixed vs. Intestinal)

1.697 (1.238–2.326)

1.554 (1.242–1.943)

 T1

0.306 (0.149–0.629)

0.265 (0.121–0.581)

 T2

0.318 (0.178–0.566)

0.341 (0.191–0.608)

 T3

0.442 (0.306–0.638)

0.445 (0.308–0.645)

 T4a

0.779 (0.581–1.045)

0.791 (0.589–1.062)

 T4b

Reference

Reference

 N0

0.216 (0.146–0.321)

0.218 (0.147–0.323)

 N1

0.428 (0.300–0.612)

0.413 (0.287–0.595)

 N2

0.561 (0.408–0.770)

0.580 (0.421–0.799)

 N3a

0.670 (0.505–0.888)

0.699 (0.526–0.928)

 N3b

Reference

Reference

 Distant metastasis

2.473 (1.920–3.186)

2.503 (1.941–3.228)