Fig. 5: Automated Design of Synthetic Promoters. | Nature Communications

Fig. 5: Automated Design of Synthetic Promoters.

From: Automated model-predictive design of synthetic promoters to control transcriptional profiles in bacteria

Fig. 5

A Promoter sequences were forward engineered with desired transcription rates and start sites. B Sequence analysis of the 75 bp forward engineered promoters showed low sequence similarity. C Model predictions are compared to in vivo transcription rate measurements for the 35 designed promoters (R2 = 0.80, Spearman’s ρ = 0.89). Red dots denote the mean of duplicate measurements (n = 2 biological replicates). Data are provided in Supplementary Data 1.

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