Table 3 AUC (95% CI) of chronological age, sex, and epigenetic frailty risk score in prediction of being frail at baseline and each follow-up
Categories | AUC (95% CI) | P a |
|---|---|---|
Subset III (ESTHER study) | ||
F-BL | ||
Age, sex | 0.629 (0.566–0.692) | |
eFRS | 0.702 (0.641–0.763) | |
Age, sex, eFRS | 0.711 (0.652–0.770) | 0.01 |
F-2Y | ||
Age, sex | 0.644 (0.584–0.704) | |
eFRS | 0.666 (0.607–0.724) | |
Age, sex, eFRS | 0.682 (0.625–0.739) | 0.07 |
F-5Y | ||
Age, sex | 0.650 (0.591–0.708) | |
eFRS | 0.658 (0.602–0.714) | |
Age, sex, eFRS | 0.680 (0.624–0.736) | 0.04 |
F-8Y | ||
Age, sex | 0.661 (0.601–0.720) | |
eFRS | 0.631 (0.571–0.691) | |
Age, sex, eFRS | 0.671 (0.613–0.729) | 0.31 |
F-11Y | ||
Age, sex | 0.689 (0.621–0.756) | |
eFRS | 0.595 (0.522–0.668) | |
Age, sex, eFRS | 0.691 (0.624–0.758) | 0.38 |
Subset IV (KORA-Age study) | ||
F-BL | ||
Age, sex | 0.741 (0.702–0.780) | |
eFRS | 0.620 (0.579–0.662) | |
Age, sex, eFRS | 0.745 (0.706–0.784) | 0.23 |
F-4Y | ||
Age, sex | 0.715 (0.676–0.755) | |
eFRS | 0.630 (0.588–0.672) | |
Age, sex, eFRS | 0.720 (0.681–0.760) | 0.03 |
F-8Y | ||
Age, sex | 0.759 (0.717–0.801) | |
eFRS | 0.638 (0.592–0.685) | |
Age, sex, eFRS | 0.763 (0.721–0.804) | 0.44 |
