Table 1 Identification of otosclerosis cases in the study cohorts based on ICD codes, procedure codes and self-reported data
Classification | Code(s) | Definition | FinnGen | EstBB | UKBB |
|---|---|---|---|---|---|
ICD-10 | H80 | Otosclerosis (any) | — | 328 | — |
ICD-10 | H80.0 | .. Involving oval window, nonobliterative | 740 | 362 | 10 |
ICD-10 | H80.1 | .. Involving oval window, obliterative | 223 | 90 | 3 |
ICD-10 | H80.2 | .. Cochlear | 55 | 49 | 3 |
ICD-10 | H80.8 | .. Other | 146 | 139 | 6 |
ICD-10 | H80.9 | .. Unspecified | 742 | 512 | 304 |
ICD-9 | 387 | Otosclerosis (any) | 306 | — | 36 |
ICD-8 | 386 | Otosclerosis (any) | 313 | — | — |
Phecode | 383 | Otosclerosis (any) | 1563 | 985 | 353 |
Self-report | Otosclerosis (any) | — | — | 203 | |
Self-report | Stapes procedure (any) | — | — | 266 | |
Procedure codes | DDA00, 61006 | Stapedotomy | 517 | 218 | — |
Procedure codes | DDB00, D171, D172 | Stapedectomy | 129 | — | 464 |
Any stapes procedure | Self-report or procedure code -based | 616 | 218 | 700 | |
Total cases | 1563 | 985 | 956 | ||
Total controls | 249281 | 196516 | 415401 | ||
Prevalence (%) | 0.62 | 0.50 | 0.23 |
