Fig. 4: A sequence of activity occurs across thalamic nuclei during behavioral arousal. | Nature Communications

Fig. 4: A sequence of activity occurs across thalamic nuclei during behavioral arousal.

From: A temporal sequence of thalamic activity unfolds at transitions in behavioral arousal state

Fig. 4: A sequence of activity occurs across thalamic nuclei during behavioral arousal.

a The relative timing of thalamic activation differs significantly across nuclei (mean lag shown by the solid vertical line; shading is 95% confidence interval, colored from red to purple based on the order in sequence). Zero represents the timing of the whole thalamus (dashed line). The centromedian (CM, red) and ventral posterolateral (VPL, orange) thalamic nuclei lead the rest of the thalamus during behavioral arousal, while the ventral anterior (VA, light blue), anteroventral (AV, dark blue), and ventral lateral anterior (VLA, purple) lag behind. b Image of mean lag times per nucleus in one subject. Color represents precise lag. c The activation onset times (arrows) and the hemodynamic response (solid lines) show a sequence in activation across nuclei. Color represents the order in a lag sequence. d Thalamic nuclei activation onset is sequenced similarly to the lag values. Source data are provided in the “Fig. 4 Source Data” file.

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