Fig. 6: Antithrombogenicity of the pCBM/pSB hydrogel coatings in vitro and ex vivo blood circulation in rat model.
From: Microgel reinforced zwitterionic hydrogel coating for blood-contacting biomedical devices
a Scheme of circulation calcified whole blood in vitro. b Cross-section, (c) photographs, and (d) thrombus weight of circuits of PVC tubing and pCBM/pSB hydrogel coating modified PVC tubing after circulation for 1 h (n = 3). e Scheme of an ex vivo perfusion experiment in SD rats. f Cross-section, (g) photographs, and (h) thrombus weight of circuits of PVC tubing and pCBM/pSB hydrogel coating modified PVC tubing after circulation for 1 h without anticoagulants (n = 3). Data presented as mean ± SD and analyzed using a one-way ANOVA with Tukey’s post hoc test in (d, h), **P < 0.01. d P = 0.0036 (PVC vs pCBM/pSB, in vitro blood circulation), h P = 0.0049 (PVC vs pCBM/pSB, ex vivo blood circulation). Source data are provided as a Source Data file.
