Fig. 6: Structural polymorphism of the LPA1-Gi interface. | Nature Communications

Fig. 6: Structural polymorphism of the LPA1-Gi interface.

From: Structure of the active Gi-coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist

Fig. 6

a Density maps of the 3.5 Å resolution stable state and S1–4. b Comparison of the stable state, S1, and S2. c Comparison of the stable state, S3, and S4. d Superimposition of the stable state and S1–4, aligned at the receptor. TM5 is omitted. e Superimposition of the Gαi1 subunits in the stable state, S1–4, and the GDP-bound inactive Gi heterotrimer (PDB 1GG2).

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