Fig. 2: Overall structure of the Tapasin–B44:05–6mer complex.
From: Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation
a Ribbon representation of Tapasin (magenta), B44:05 heavy (α) chain (blue), and β2m light chain (lime). b Similar to a, but with B44:05 α and β2m in surface display. c tapasin in surface display. d Interface residues of B44:05 α and β2m in surface display, with residues colored and numbered. e Interface residues of Tapasin as indicated. f Rotated view of the membrane proximal trimer of B44:05 α3 domain (blue), β2m (lime), and Tapasin IgC domain (magenta). BSA Buried surface area.
