Table 2 Pharmacokinetics profiles according to sialic acid content of IgETRAP

From: Combined IgE neutralization and Bifidobacterium longum supplementation reduces the allergic response in models of food allergy

Sialic acid content (mol mol−1)

T1/2 (hr)

Tmax (hr)

Cmax (μg mL−1)

AUClast (hr·µg mL−1)

AUC0~∞ (hr·μg mL−1)

10.3

37.6

3

1.5 ± 0.5

62.0 ± 5.5

62.7

14.9

34.8

10

2.6 ± 0.2

197.3 ± 5.6

199.0

21.4

39.9

10

12.1 ± 0.7

953.9 ± 45.1

969.5

  1. T1/2, half-life; Tmax, Time of maximum concentration observed; Cmax, maximum concentration observed; AUClast, area under the curve from time zero to time of last measurable concentration; AUC0~∞, area under the curve from time zero to infinity.
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