Fig. 4: JAK2 activation of HOXA9 improves colony survival in response to HOXA9 inhibition.
From: HOXA9 has the hallmarks of a biological switch with implications in blood cancers

a The ratios of colonies produced per sample are expressed as Scrambled:shHOXA9 colony number ratio with means. b The normalised colony count per sample and per condition with means and interquartile ranges of the three replicates. Two-way ANOVA statistical tests using multiple comparisons with FDR correction indicate a significant increase of colonies for TET2 mutant versus WT cells with shHOXA9 \((q=0.0032)\) and JAK2 mutant cells in both WT (\(q=0.0171\)) and in shHOXA9 \((q=0.0171)\) contexts. Source data are provided as a Source Data file.