Table 2 Optical mapping assessments of right ventricular free walls of control and Tmem65 KD hearts 3 weeks post viral injection

From: Tmem65 is critical for the structure and function of the intercalated discs in mouse hearts

 

Scrambled shRNA

Tmem65 shRNA

Sinus rhythm

Pace (11 Hz)

Sinus rhythm

Pace (11 Hz)

APD25 (ms)

13.1 ± 0.3

17.7 ± 1.8

13.6 ± 0.6

21.8 ± 1.0*

APD50 (ms)

23.8 ± 1.1

26.1 ± 1.4

24.5 ± 1.6

30.8 ± 1.0*

APD80 (ms)

48.3 ± 1.3

39.7 ± 3.3

47.8 ± 2.3

42.1 ± 1.1

Time-to-peak (ms)

6.8 ± 0.4

9.8 ± 0.2

7.4 ± 0.8

11.8 ± 0.4*

  1. Four male and 2 female mice in Tmem65 group; 4 female and 2 male mice in Tmem65 group.
  2. APD action potential duration.
  3. *p < 0.05.
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