Fig. 7: Gene association network analysis reveals TME modules for therapeutic targeting. | Nature Communications

Fig. 7: Gene association network analysis reveals TME modules for therapeutic targeting.

From: The spatial transcriptomic landscape of non-small cell lung cancer brain metastasis

Fig. 7: Gene association network analysis reveals TME modules for therapeutic targeting.The alternative text for this image may have been generated using AI.

a–c Snapshots of the gene association networks in the TBME (a), TIME-B (b), and TIME-L (c) based on the corresponding DEGs. Functional modules are identified by broken circles. Network DEGs colored from blue to red according to Log2FC scale −3 to 3. FC, fold change. d A ligand–receptor interaction network between LB and TBME. e A list of FDA-approved drug targets identified from the DEG and network analysis.

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