Fig. 5: Model of crossover patterning via HEI10 coarsening.
From: Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage
HEI10 (red) is captured at the middle of the SC and coarsens into large pro-CO foci. The number of large pro-CO foci is determined by SC length (heterochiasmy), and HEI10 expression levels. HEI10 overexpression increases CO number, and weakens interference but maintains heterochiasmy. In absence of an SC (zyp1), HEI10 is exchanged directly between the foci and the nucleoplasm abolishing both interference and heterochiasmy, and the number of foci depends on HEI10 expression level. Created with BioRender.com.
