Fig. 2: scRNA-seq analysis of the dynamic changes in T cell subsets.
From: Multicellular immune dynamics implicate PIM1 as a potential therapeutic target for uveitis
a t-SNE plots of T cell subsets from all mice groups. b Heatmap showing scaled expression of discriminative gene sets for T cell subsets from all mice groups. c t-SNE plots of canonical markers for T cell subsets from all mice groups. d Line charts showing the proportion of T cell subsets in total T cells from EAU and control groups at different time points. e Line charts showing the mean expression of Pim1 in T cell subsets from EAU and control groups at different time points. f Heatmap showing representative GO terms and KEGG pathways enriched in upregulated DEGs of the T cell subsets in the D14c/D0 comparison groups at different time points. Significance was calculated based on the accumulative hypergeometric distribution by Metascape webtool. g Heatmap showing representative GO terms and KEGG pathways enriched in upregulated DEGs of the T cell subsets in the D14/D14c comparison groups at different time points. Significance was calculated based on the accumulative hypergeometric distribution by Metascape webtool.
