Fig. 5: General protocol of our proposed domain knowledge integrated deep learning method. | Nature Communications

Fig. 5: General protocol of our proposed domain knowledge integrated deep learning method.

From: Using domain knowledge for robust and generalizable deep learning-based CT-free PET attenuation and scatter correction

Fig. 5

We decomposed the complex end-to-end generation from non-attenuation and non-scatter corrected images (NASC-PET) to corrected images (ASC-PET) into two components, anatomy-independent textures (relating to tracers and diseases) and anatomy-dependent correction, and regularized a 3D deep neural network to estimate this low-frequency anatomy-dependent correction information only.

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